SLC16A8 - solute carrier family 16 member 8 Gene

Also Known as MCT3; REMP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23539

About SLC16A8

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,078,137-38,084,184 (from NCBI)

This gene has 4 transcripts (splice variants), 170 orthologues and 13 paralogues. Broad expression in prostate (RPKM 2.1), testis (RPKM 0.9) and 20 other tissues.

Summary

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010]

SLC16A8 Products (2)

mRNA Protein Name
NM_001394131.1 NP_001381060.1 monocarboxylate transporter 3 isoform 2
NM_013356.3 NP_037488.2 monocarboxylate transporter 3 isoform 1

SLC16A8 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (26 - 328)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 504 a.a.
Protein Preferred Names Protein Names

monocarboxylate transporter 3

  • MCT 3

Related Diseases

Diseases Alias
Macular Degeneration, Age-Related, 1
  • Macular Degeneration

  • Age-Related Macular Degeneration

  • Macular Degeneration, Age-Related

  • Age Related Macular Degeneration

  • Age Related Macular Degeneration 1

  • ARMD1

  • Senile Macular Degeneration

  • Maculopathy, Age-Related, 1

  • Macular Degeneration, Age-Related, Reduced Risk Of

  • Age Related Maculopathy 1

  • Age Related Maculopathies

  • Age Related Maculopathy

  • Senile Macular Retinal Degeneration

  • Macular Degeneration Of Retina

  • Age-Related Maculopathy

  • Amd

  • Armd

  • Age-Related Maculopathy, Susceptibility To

  • Maculopathy Age-Related

  • Macular Degeneration, Age-Related, 1, Susceptibility To

  • Maculopathy, Age-Related

  • Macular Degeneration, Age-Related, Type 1

  • Macular Degeneration, Age-Related, 2

Fundus Dystrophy
  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal

Retinitis Pigmentosa
  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus SLC16A8 VGNC VGNC:65215
Macaca mulatta SLC16A8 VGNC VGNC:108037
Canis familiaris SLC16A8 VGNC VGNC:46246
Rattus norvegicus SLC16A8 RGD RGD:69282
Mus musculus SLC16A8 MGD MGI:1929519
Bos taurus SLC16A8 VGNC VGNC:34694
Others SLC16A8 NCBI