2. Gene
  3. Nek4 - NIMA (never in mitosis gene a)-related expressed kinase 4 Gene

Nek4 - NIMA (never in mitosis gene a)-related expressed kinase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Stk2

Gene ID: 23955 | Gene type: protein coding

About Nek4

Summary

Enables manganese ion binding activity and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cytoplasm. Is expressed in seminiferous tubule; spermatid; spermatocyte; and testis. Orthologous to human NEK4 (NIMA related kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Nek4 Products(2)

mRNA Protein Name
NM_001308328.1 NP_001295257.1 serine/threonine-protein kinase Nek4 isoform 2
NM_011849.3 NP_035979.1 serine/threonine-protein kinase Nek4 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables manganese ion binding IDA
IDA: Inferred from direct assay
10529384 MGI
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
10529384 MGI
Biological Process GO Annotation Evidence Reference Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
10529384 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10529384 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase Nek4

serine/threonine-protein kinase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-183068 AP4-43 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nek4 NCBI NCBI:6787