2. Gene
  3. Pnldc1 - poly(A)-specific ribonuclease (PARN)-like domain containing 1 Gene

Pnldc1 - poly(A)-specific ribonuclease (PARN)-like domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm313

Gene ID: 240023 | Gene type: protein coding

About Pnldc1

Summary

Enables poly(A)-specific ribonuclease activity. Involved in nuclear-transcribed mRNA poly(A) tail shortening. Acts upstream of or within blastocyst formation. Located in endoplasmic reticulum. Is expressed in several structures, including early conceptus; gonad; and skin. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human PNLDC1 (PARN like ribonuclease domain containing exonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Pnldc1 Products(1)

mRNA Protein Name
NM_001034866.1 NP_001030038.1 poly(A)-specific ribonuclease PNLDC1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables poly(A)-specific ribonuclease activity IDA
IDA: Inferred from direct assay
27515512 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within blastocyst formation IMP
IMP: Inferred from mutant phenotype
27869233 MGI
involved in nuclear-transcribed mRNA poly(A) tail shortening IDA
IDA: Inferred from direct assay
27515512 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
27515512 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

poly(A)-specific ribonuclease PNLDC1

PARN-like domain-containing protein 1

poly(A)-specific ribonuclease PARN-like domain-containing protein 1

poly(A)-specific ribonuclease domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10779 PNLDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pnldc1 NCBI NCBI:154197