2. Gene
  3. Agbl1 - ATP/GTP binding protein-like 1 Gene

Agbl1 - ATP/GTP binding protein-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ccp4; Nna1-l1; EG244071; D430020F16

Gene ID: 244071 | Gene type: protein coding

About Agbl1

Summary

Enables metallocarboxypeptidase activity and tubulin binding activity. Involved in C-terminal protein deglutamylation and protein side chain deglutamylation. Predicted to be located in cytosol. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy. Orthologous to human AGBL1 (AGBL Carboxypeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Agbl1 Products(1)

mRNA Protein Name
NM_001199224.1 NP_001186153.1 cytosolic carboxypeptidase 4
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables metallocarboxypeptidase activity IDA
IDA: Inferred from direct assay
21074048 MGI
enables metallocarboxypeptidase activity IMP
IMP: Inferred from mutant phenotype
21074048 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21074048 MGI
enables tubulin binding IDA
IDA: Inferred from direct assay
21074048 MGI
Biological Process GO Annotation Evidence Reference Source
involved in C-terminal protein deglutamylation IDA
IDA: Inferred from direct assay
21074048 MGI
involved in C-terminal protein deglutamylation IMP
IMP: Inferred from mutant phenotype
21074048 MGI
involved in protein side chain deglutamylation IDA
IDA: Inferred from direct assay
21074048 MGI
involved in protein side chain deglutamylation IMP
IMP: Inferred from mutant phenotype
21074048 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytosolic carboxypeptidase 4

protein deglutamylase CCP4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00440 AGBL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agbl1 NCBI NCBI:123624