Slc34a3 - solute carrier family 34 member 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246234

Summary

Enables sodium:phosphate symporter activity. Involved in response to magnesium ion; response to nutrient levels; and sodium-dependent phosphate transport. Located in apical plasma membrane; brush border membrane; and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in hereditary hypophosphatemic rickets with hypercalciuria. Orthologous to human SLC34A3 (solute carrier family 34 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc34a3 Products (1)

mRNA Protein Name
NM_139338.3 NP_647554.2 sodium-dependent phosphate transport protein 2C

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sodium:phosphate symporter activity IMP
IMP: Inferred from mutant phenotype
11880379 RGD
Biological Process GO Annotation Evidence References Source
involved in phosphate ion transport IMP
IMP: Inferred from mutant phenotype
11880379 RGD
involved in response to magnesium ion IEP
IEP: Inferred from expression pattern
18701629 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
12851820 RGD
involved in sodium-dependent phosphate transport IMP
IMP: Inferred from mutant phenotype
18586044 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11880379 RGD
located in brush border membrane IDA
IDA: Inferred from direct assay
11880379 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent phosphate transport protein 2C

  • Na(+)-dependent phosphate cotransporter 2C

  • Na(+)/Pi cotransporter 2C

  • Na+/Pi-cotransporter type IIc

  • naPi-2c

  • sodium-phosphate transport protein 2C

  • sodium/phosphate cotransporter 2C

  • solute carrier family 34 (sodium phosphate), member 3

  • solute carrier

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13194 SLC34A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc34a3 NCBI NCBI:142680