Ppp2cb - protein phosphatase 2 catalytic subunit beta Gene

Also Known as Pp2a2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24673

Summary

Enables protein C-terminus binding activity and protein serine/threonine Phosphatase activity. Involved in several processes, including negative regulation of Ras protein signal transduction; positive regulation of microtubule binding activity; and response to lead ion. Predicted to be located in cytoplasm. Predicted to be part of protein Phosphatase type 2A complex. Orthologous to human PPP2CB (protein Phosphatase 2 catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2cb Products (1)

mRNA Protein Name
NM_017040.3 NP_058736.1 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables phosphoprotein phosphatase activity IDA
IDA: Inferred from direct assay
9792806 RGD
enables protein serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
11884620 RGD
enables protein serine/threonine phosphatase activity IMP
IMP: Inferred from mutant phenotype
10640627 RGD
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
16519540 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of Ras protein signal transduction IDA
IDA: Inferred from direct assay
11884620 RGD
involved in protein dephosphorylation IDA
IDA: Inferred from direct assay
16519540 RGD
involved in response to lead ion IDA
IDA: Inferred from direct assay
22387731 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

  • PP2A-beta

  • protein phosphatase 2, catalytic subunit, beta isozyme

  • protein phosphatase 2A catalytic alpha subunit

  • protein phosphatase-2A-beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11008 PPP2CB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp2cb NCBI NCBI:5516