Ppp2cb - protein phosphatase 2 catalytic subunit beta Gene

Rattus norvegicus

Also known as Pp2a2

Gene ID: 24673 | Gene type: protein coding

About Ppp2cb

Summary

Enables protein C-terminus binding activity and protein serine/threonine Phosphatase activity. Involved in several processes, including negative regulation of Ras protein signal transduction; positive regulation of microtubule binding activity; and response to lead ion. Predicted to be located in cytoplasm. Predicted to be part of protein Phosphatase type 2A complex. Orthologous to human PPP2CB (protein Phosphatase 2 catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2cb Products(1)

mRNA	Protein	Name
NM_017040.3	NP_058736.1	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables phosphoprotein phosphatase activity	IDA IDA: Inferred from direct assay	9792806	RGD
enables protein serine/threonine phosphatase activity	IDA IDA: Inferred from direct assay	11884620	RGD
enables protein serine/threonine phosphatase activity	IMP IMP: Inferred from mutant phenotype	10640627	RGD
enables transmembrane transporter binding	IPI IPI: Inferred from physical interaction	16519540	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of Ras protein signal transduction	IDA IDA: Inferred from direct assay	11884620	RGD
involved in protein dephosphorylation	IDA IDA: Inferred from direct assay	16519540	RGD
involved in response to lead ion	IDA IDA: Inferred from direct assay	22387731	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

PP2A-beta	protein phosphatase 2, catalytic subunit, beta isozyme
protein phosphatase 2A catalytic alpha subunit	protein phosphatase-2A-beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11008	PPP2CB Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ppp2cb	NCBI	NCBI:5516

Name
Email *

	Sorry, but the email address you supplied was invalid.