Onecut1 - one cut homeobox 1 Gene

Rattus norvegicus

Also known as Hnf6

Gene ID: 25231 | Gene type: protein coding

About Onecut1

Summary

Enables DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in glucose metabolic process and positive regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human ONECUT1 (one cut homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Onecut1 Products(1)

mRNA	Protein	Name
NM_022671.3	NP_073162.2	hepatocyte nuclear factor 6

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IMP IMP: Inferred from mutant phenotype	8790352	RGD
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	20735474	RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	9593691	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in glucose metabolic process	IMP IMP: Inferred from mutant phenotype	8790352	RGD
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	20735474	RGD
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	9593691	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

hepatocyte nuclear factor 6

HNF-6

one cut domain, family member 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09785	ONECUT1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Onecut1	NCBI	NCBI:3175

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