Abcc9 - ATP binding cassette subfamily C member 9 Gene

Also Known as Sur2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25560

Summary

Enables several functions, including identical protein binding activity; sulfonylurea receptor activity; and syntaxin binding activity. Contributes to cation channel activity. Involved in potassium ion import across plasma membrane; response to ATP; and response to xenobiotic stimulus. Located in T-tubule; acrosomal vesicle; and mitochondrion. Part of inward rectifying Potassium Channel. Biomarker of Parkinsonism; hypertension; and sciatic neuropathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1O; familial atrial fibrillation; and hypertrichotic osteochondrodysplasia Cantu type. Orthologous to human ABCC9 (ATP binding cassette subfamily C member 9). [provided by Alliance of Genome Resources, Apr 2022]

Abcc9 Products (1)

mRNA Protein Name
NM_013040.3 NP_037172.2 ATP-binding cassette sub-family C member 9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATPase-coupled monoatomic cation transmembrane transporter activity IGI
IGI: Inferred from genetic interaction
28842488 RGD
enables heterocyclic compound binding IPI
IPI: Inferred from physical interaction
23078514 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
23253866 RGD
enables potassium channel activator activity IMP
IMP: Inferred from mutant phenotype
26621776 RGD
enables potassium channel regulator activity IDA
IDA: Inferred from direct assay
8630239 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19491242 RGD
enables sulfonylurea receptor activity IDA
IDA: Inferred from direct assay
8630239 RGD
enables syntaxin binding IPI
IPI: Inferred from physical interaction
15339904 RGD
Biological Process GO Annotation Evidence References Source
involved in inorganic cation transmembrane transport IGI
IGI: Inferred from genetic interaction
28842488 RGD
involved in monoatomic cation transmembrane transport IMP
IMP: Inferred from mutant phenotype
26621776 RGD
involved in potassium ion import across plasma membrane IDA
IDA: Inferred from direct assay
8630239 RGD
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
10347249 RGD
involved in potassium ion transport IDA
IDA: Inferred from direct assay
11567030 RGD
involved in response to ATP IGI
IGI: Inferred from genetic interaction
26621776 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15964031 RGD
Cellular Component GO Annotation Evidence References Source
located in T-tubule IDA
IDA: Inferred from direct assay
15647111 RGD
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
21328565 RGD
part of inward rectifying potassium channel IDA
IDA: Inferred from direct assay
8630239 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family C member 9

  • ATP-binding cassette transporter sub-family C member 9

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 9

  • ATP-binding cassette, sub-family C, member 9-like

  • ATP-binding cassette, subfamily C (CFTR/MRP), member 9

  • Sulfonylurea receptor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00067 ABCC9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22364 Abcc9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcc9 NCBI NCBI:10060