Hck - HCK proto-oncogene, Src family tyrosine kinase Gene

Also Known as Hctk; p56Hck; p59Hck

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25734

Summary

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types.The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms in human and mouse. Based on strong sequence conservation amongst these species, this may also be true for rat. [provided by RefSeq, Jul 2008]

Hck Products (1)

mRNA Protein Name
NM_013185.3 NP_037317.2 tyrosine-protein kinase HCK
Protein Preferred Names Protein Names

tyrosine-protein kinase HCK

  • hematopoietic cell kinase

  • hemopoietic cell kinase

  • hemopoietic cell tyrosine kinase

  • p56-HCK

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-157442 GLPG3312 Inhibitor 98.63% Phase 1

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175451 MRT-10350 Degrader 99.10% Unkown
HY-181050 DFCI-002-06 Degrader / Unkown
HY-178950 Hck-IN-3 Inhibitor / Unkown
HY-176194 Antifibrotic agent 1 Inhibitor / Unkown
HY-175437 MRT-7612 Degrader / Unkown
HY-178014 SIK1-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hck NCBI NCBI:3055