MRT-7612
MRT-7612 (Compound 4) is a cereblon-based tyrosine kinases molecular glue degrader. MRT-7612 significantly induces HCK and LYN degradation, with week efficacy on LCK. MRT-7612 can be used for cancers like chronic myeloid leukemia, autoimmune and chronic inflammatory diseases research.
For research use only. We do not sell to patients.
- Formula: C25H24N4O4
- Molecular Weight:444.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Hck |
Lck |
Lyn |
Chemical Information
-
Molecular Weight 444.48
-
Formula C25H24N4O4
-
SMILES
O=C(N1CC2(CCC3=C2C=CC=C3)C1)NC4=CC5=C(C(N(C(CC6)C(NC6=O)=O)C5)=O)C=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)