2. Gene
  3. NAAA - N-acylethanolamine acid amidase Gene

NAAA - N-acylethanolamine acid amidase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PLT; ASAHL

Gene ID: 27163 | Gene type: protein coding

About NAAA

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:75,910,655-75,941,013 (from NCBI)

This gene has 9 transcripts (splice variants), 199 orthologues and 1 paralogue. Broad expression in prostate (RPKM 15.8), colon (RPKM 14.0) and 24 other tissues.

Summary

This gene encodes an N-acylethanolamine-hydrolyzing Enzyme which is highly similar to acid Ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

NAAA Products(3)

mRNA Protein Name
NM_001042402.2 NP_001035861.1 N-acylethanolamine-hydrolyzing acid amidase isoform 2 precursor
NM_001363719.2 NP_001350648.1 N-acylethanolamine-hydrolyzing acid amidase isoform 2 precursor
NM_014435.4 NP_055250.2 N-acylethanolamine-hydrolyzing acid amidase isoform 1 precursor

NAAA Protein Structure

NAAA-beta

NAAA-beta: beta subunit of N-acylethanolamine-hydrolyzing acid amidase (33 - 121)

CBAH

CBAH: Linear amide C-N hydrolases, choloylglycine hydrolase family (126 - 292)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
Protein Preferred Names Protein Names

N-acylethanolamine-hydrolyzing acid amidase

ASAH-like protein

Recombinant NAAA Proteins

Cat. No. Product Name Accession Purity
HY-P79154 ASAHL Protein, Human (V151I, CHO, His) Q02083 (M1-K359, V151I) ≥95%

Related Diseases

Diseases Alias
Bleeding Disorder, Platelet-Type, 12

BDPLT12

Prostaglandin-Endoperoxide Synthase 1 Deficiency, Platelet

Pghs1 Deficiency

Platelet Cyclooxygenase 1 Deficiency

Platelet Cox1 Deficiency

Platelet-Type Bleeding Disorder 12

Platelet Prostaglandin-Endoperoxide Synthase 1 Deficiency
Vulvar Syringoma
Noonan Syndrome 10

NS10

Noonan Syndrome, Type 10
Charcot-Marie-Tooth Disease, Type 4j

Charcot-Marie-Tooth Disease Type 4j

CMT4J

Charcot-Marie-Tooth Disease, Autosomal Recessive, Type 4j

Autosomal Recessive Charcot-Marie-Tooth Disease Type 4j

Charcot-Marie-Tooth Disease 4j
Yunis-Varon Syndrome

Cleidocranial Dysplasia With Micrognathia, Absent Thumbs, And Distal Aphalangia

Yunis Varon Syndrome

YVS

Cleidocranial Dysplasia-Micrognathia-Absent Thumbs Syndrome

Cleidocranial Dysplasia, Micrognathia, Absent Thumbs, & Distal Aphalangia

Yunis-Varón Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0182 Carmofur Inhibitor 99.95% Unkown
Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-145339 ARN19702 99.60% Unkown
HY-120813 ARN 077 Inhibitor 99.77% Unkown
HY-147773 NAAA-IN-1 99.65% Unkown
HY-124597 ARN726 95.00% Unkown
HY-132882 ARN19689 Inhibitor / Unkown
HY-120813A ARN 077 (enantiomer) Inhibitor 99.71% Unkown
HY-121975 N-Cyclohexanecarbonylpentadecylamine / Unkown
HY-147775 NAAA-IN-3 / Unkown
HY-D2338 PMBD / Unkown
HY-RS08993 NAAA Human Pre-designed siRNA Set A / Unkown
HY-157223 ARN16186 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NAAA VGNC VGNC:75068
Mus musculus NAAA MGD MGI:1914361
Felis catus NAAA VGNC VGNC:68327
Bos taurus NAAA VGNC VGNC:31854
Rattus norvegicus NAAA RGD RGD:1307267