2. Gene
  3. Hsd17b6 - hydroxysteroid (17-beta) dehydrogenase 6 Gene

Hsd17b6 - hydroxysteroid (17-beta) dehydrogenase 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rdh8; Hsd17b9; 17betaHSD9

Gene ID: 27400 | Gene type: protein coding

About Hsd17b6

Summary

Enables steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in brexanolone catabolic process. Predicted to act upstream of or within steroid metabolic process. Predicted to be located in endoplasmic reticulum; endosome; and membrane. Orthologous to human HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b6 Products(2)

mRNA Protein Name
NM_001359377.1 NP_001346306.1 17-beta-hydroxysteroid dehydrogenase type 6 precursor
NM_013786.3 NP_038814.1 17-beta-hydroxysteroid dehydrogenase type 6 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables 5alpha-androstane-3beta,17beta-diol dehydrogenase activity IDA
IDA: Inferred from direct assay
10537158 MGI
enables androstan-3-alpha,17-beta-diol dehydrogenase activity IDA
IDA: Inferred from direct assay
10537158 MGI
enables androsterone dehydrogenase activity IDA
IDA: Inferred from direct assay
10537158 MGI
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IDA
IDA: Inferred from direct assay
10537158 MGI
enables testosterone 17-beta-dehydrogenase (NADP+) activity IDA
IDA: Inferred from direct assay
10537158 MGI
enables testosterone dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
10537158 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

17-beta-hydroxysteroid dehydrogenase type 6

17-beta-HSD 6

17-beta-HSD6

17-beta-HSD9

3-alpha->beta-HSE

3-alpha->beta-hydroxysteroid epimerase

hydroxysteroid (17-beta) dehydrogenase 9

oxidative 3-alpha hydroxysteroid dehydrogenase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06398 HSD17B6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd17b6 NCBI NCBI:8630