2. Gene
  3. AQP4 - aquaporin 4 Gene

AQP4 - aquaporin 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus

Also known as MIWC; WCH4; AQP-4

Gene ID: 281008 | Gene type: protein coding

About AQP4

Summary

This gene encodes a member of the Aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant Aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

AQP4 Products(3)

mRNA Protein Name
NM_001317792.2 NP_001304721.1 aquaporin-4 isoform Ax
NM_001317794.2 NP_001304723.1 aquaporin-4 isoform B
NM_181003.4 NP_851346.1 aquaporin-4 isoform A
Protein Preferred Names Protein Names

aquaporin-4

mercurial-insensitive water channel

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-115460 AER-271 96.90% Phase 1
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W008574 TGN-020 99.97% Unkown
HY-W008574A TGN-020 sodium 99.96% Unkown
HY-W176557 TGN-073 99.53% Unkown
HY-P10936A AQP4 (201-220) TFA 99.91% Unkown
HY-N10756 Hyp9 Agonist 99.90% Unkown
HY-N4246 Bacopaside I 99.20% Unkown
HY-157226 ORI-TRN-002 Inhibitor / Unkown
HY-RS00876 AQP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W017091 3-Phenoxy-1,2-propanediol Inhibitor 95.0% Unkown
HY-18805 Nicotinanilide Inhibitor 99.84% Unkown
HY-P10936 AQP4 (201-220) / Unkown
HY-P10937 AQP4 (205-215) / Unkown
HY-P10937A AQP4 (205-215) TFA / Unkown
HY-RS16702 Aqp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23136 Aqp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991869 Aquaporumab Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens AQP4 NCBI NCBI:361
Mus musculus AQP4 NCBI NCBI:11829