AQP4 (205-215)
AQP4 (205-215) is a fragment of Aquaporin-4 (AQP4). AQP4 is a neuromyelitis optica autoantigen that is upregulated and presented in B cells after engagement of CD40. AQP4 is associated with autoimmune inflammatory diseases of the central nervous system (CNS), neuromyelitis optica (NMO).
For research use only. We do not sell to patients.
- CAS No.: 2891466-35-4
- Formula: C48H75N13O17S
- Molecular Weight:1138.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2891466-35-4
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Molecular Weight 1138.25
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Formula C48H75N13O17S
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Sequence
Ile-Asn-Tyr-Thr-Gly-Ala-Ser-Met-Asn-Pro-Ala
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Sequence Shortening
INYTGASMNPA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ali Maisam Afzali, et al. B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature. 2024 Mar;627(8003):407-415. [Content Brief]
[2]. Anna-Lena Vogel, et al. Deletional tolerance prevents AQP4-directed autoimmunity in mice. Eur J Immunol. 2017 Mar;47(3):458-469. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)