Hoxd13 - homeo box D13 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 288154

Summary

Enables sequence-specific double-stranded DNA binding activity. Involved in embryonic hindgut morphogenesis; prostate gland development; and response to testosterone. Located in nucleus. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in brachydactyly-syndactyly syndrome; clubfoot; cryptorchidism; and dysostosis (multiple). Orthologous to human HOXD13 (homeobox D13). [provided by Alliance of Genome Resources, Apr 2022]

Hoxd13 Products (1)

mRNA Protein Name
NM_001105886.1 NP_001099356.1 homeobox protein Hox-D13

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
19925654 RGD
Biological Process GO Annotation Evidence References Source
involved in embryonic hindgut morphogenesis IMP
IMP: Inferred from mutant phenotype
17161201 RGD
involved in prostate gland development IEP
IEP: Inferred from expression pattern
17138648 RGD
involved in response to testosterone IEP
IEP: Inferred from expression pattern
17138648 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-D13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06326 HOXD13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxd13 NCBI NCBI:3239