2. Gene
  3. Pde6b - phosphodiesterase 6B Gene

Pde6b - phosphodiesterase 6B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 289878 | Gene type: protein coding

About Pde6b

Summary

Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity. Involved in retinal cell apoptotic process. Predicted to be located in photoreceptor outer segment. Predicted to be active in photoreceptor outer segment membrane. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 2 and retinitis pigmentosa 40. Orthologous to human PDE6B (phosphodiesterase 6B). [provided by Alliance of Genome Resources, Apr 2022]

Pde6b Products(1)

mRNA Protein Name
NM_001106024.1 NP_001099494.1 rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in retinal cell apoptotic process IMP
IMP: Inferred from mutant phenotype
31009522 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide

phosphodiesterase 6B, cGMP-specific, rod, beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10233 PDE6B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde6b NCBI NCBI:5158