Psenen - presenilin enhancer gamma secretase subunit Gene

Also Known as RGD1312037

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292788

Summary

Predicted to enable endopeptidase activator activity and enzyme binding activity. Predicted to be involved in several processes, including Notch receptor processing; amyloid-beta formation; and proteolysis. Located in mitochondrion. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Orthologous to human PSENEN (presenilin enhancer, gamma-secretase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Psenen Products (1)

mRNA Protein Name
NM_001008764.2 NP_001008764.1 gamma-secretase subunit PEN-2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
20126630 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-secretase subunit PEN-2

  • LRRGT00140 mRNA

  • liver regeneration-related protein LRRGT00140

  • presenilin enhancer 2 homolog

  • presenilin enhancer protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11278 PSENEN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psenen NCBI NCBI:55851