Psenen - presenilin enhancer gamma secretase subunit Gene

Rattus norvegicus

Also known as RGD1312037

Gene ID: 292788 | Gene type: protein coding

About Psenen

Summary

Predicted to enable endopeptidase activator activity and enzyme binding activity. Predicted to be involved in several processes, including Notch receptor processing; amyloid-beta formation; and proteolysis. Located in mitochondrion. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Orthologous to human PSENEN (presenilin enhancer, gamma-secretase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Psenen Products(1)

mRNA	Protein	Name
NM_001008764.2	NP_001008764.1	gamma-secretase subunit PEN-2

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	20126630	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

gamma-secretase subunit PEN-2

LRRGT00140 mRNA	liver regeneration-related protein LRRGT00140
presenilin enhancer 2 homolog	presenilin enhancer protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11278	PSENEN Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Psenen	NCBI	NCBI:55851

Name
Email *

	Sorry, but the email address you supplied was invalid.