1. Gene
  2. Tcirg1 - T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 Gene

Tcirg1 - T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 Gene

Rattus norvegicus

Also known as OC116; TIRC7

Gene ID: 293650 | Gene type: protein coding

About Tcirg1

Summary

Predicted to enable ATPase binding activity. Predicted to be involved in vacuolar acidification. Predicted to act upstream of or within several processes, including T cell activation; animal organ development; and cellular cation homeostasis. Predicted to be located in several cellular components, including apical plasma membrane; cytoplasmic vesicle; and lysosome. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3). [provided by Alliance of Genome Resources, Apr 2022]

Tcirg1 Products(1)

mRNA Protein Name
NM_199089.3 NP_954520.3 V-type proton ATPase 116 kDa subunit a3
Protein Preferred Names Protein Names

V-type proton ATPase 116 kDa subunit a3

ATPase, H+ transporting, lysosomal V0 protein a

T cell immune response cDNA7 protein

T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3

T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a

T-cell, immun

Orthologs Information

Species Symbol Source ID
Homo sapiens Tcirg1 NCBI NCBI:10312