2. Gene
  3. Efemp2 - EGF containing fibulin extracellular matrix protein 2 Gene

Efemp2 - EGF containing fibulin extracellular matrix protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 293677 | Gene type: protein coding

About Efemp2

Summary

Predicted to enable heparin binding activity and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of vascular associated smooth muscle cell proliferation; positive regulation of aortic smooth muscle cell differentiation; and vasculature development. Predicted to act upstream of or within artery development and elastic fiber assembly. Predicted to be located in basement membrane; elastic fiber; and microfibril. Biomarker of osteoarthritis. Human ortholog(s) of this gene implicated in aortic aneurysm; arterial tortuosity syndrome; autosomal recessive cutis laxa type IB; endometrial cancer; and osteosarcoma. Orthologous to human EFEMP2 (EGF containing fibulin extracellular matrix protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Efemp2 Products(3)

mRNA Protein Name
NM_001005907.2 NP_001005907.1 EGF-containing fibulin-like extracellular matrix protein 2 isoform 2 precursor
NM_001277341.1 NP_001264270.1 EGF-containing fibulin-like extracellular matrix protein 2 isoform 1 precursor
NM_001277346.1 NP_001264275.1 EGF-containing fibulin-like extracellular matrix protein 2 isoform 3 precursor
Protein Preferred Names Protein Names

EGF-containing fibulin-like extracellular matrix protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04186 EFEMP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21849 Efemp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Efemp2 NCBI NCBI:30008