Macroh2a1 - macroH2A.1 histone Gene

Also Known as H2A.y; H2A/y; H2afy; mH2A1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29384

Summary

Predicted to enable several functions, including DNA binding activity; promoter-specific chromatin binding activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of cell differentiation; and regulation of response to oxidative stress. Predicted to act upstream of or within dosage compensation; negative regulation of transcription by RNA polymerase II; and regulation of lipid metabolic process. Located in chromatin and nucleus. Part of nucleosome. Orthologous to human MACROH2A1 (macroH2A.1 histone). [provided by Alliance of Genome Resources, Apr 2022]

Macroh2a1 Products (1)

mRNA Protein Name
NM_017182.3 NP_058878.1 core histone macro-H2A.1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
23463008 RGD
part of nucleosome IDA
IDA: Inferred from direct assay
1529340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

core histone macro-H2A.1

  • H2A histone family, member Y

  • histone macroH2A1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07947 MACROH2A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Macroh2a1 NCBI NCBI:9555