2. Gene
  3. HLA-DMB - RT1-DMb RT1 class II, locus DMb Gene

HLA-DMB - RT1-DMb RT1 class II, locus DMb Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as DMb; RT1.Mb; RT1.DMb

Gene ID: 294273 | Gene type: protein coding

About HLA-DMB

Summary

Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in peptide antigen assembly with MHC class II protein complex; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; and positive regulation of T cell proliferation. Predicted to act upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and chaperone cofactor-dependent protein refolding. Predicted to be located in late endosome membrane; lysosomal membrane; and multivesicular body. Predicted to be integral component of membrane. Predicted to be part of MHC class II protein complex. Orthologous to human HLA-DMB (major histocompatibility complex, class II, DM beta). [provided by Alliance of Genome Resources, Apr 2022]

HLA-DMB Products(1)

mRNA Protein Name
NM_198740.2 NP_942035.2 RT1 class II, DM beta precursor
Protein Preferred Names Protein Names

RT1 class II, DM beta

MHC class II-like beta chain

class II histocompatibility antigen, M beta 1 chain

major histocompatibility complex, class II, DM beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06200 HLA-DMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HLA-DMB NCBI NCBI:3109