Trpv2 - transient receptor potential cation channel, subfamily V, member 2 Gene

Also Known as Vrl1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29465

Summary

Enables identical protein binding activity. Involved in negative regulation of cell population proliferation and response to heat. Located in several cellular components, including endomembrane system; lamellipodium; and plasma membrane. Orthologous to human TRPV2 (transient receptor potential cation channel subfamily V member 2). [provided by Alliance of Genome Resources, Apr 2022]

Trpv2 Products (3)

mRNA Protein Name
NM_001270797.1 NP_001257726.1 transient receptor potential cation channel subfamily V member 2
NM_001270798.1 NP_001257727.1 transient receptor potential cation channel subfamily V member 2
NM_017207.3 NP_058903.2 transient receptor potential cation channel subfamily V member 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
1524959 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
24373766 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14991772 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
25869297 RGD
Cellular Component GO Annotation Evidence References Source
located in endomembrane system IDA
IDA: Inferred from direct assay
14991772 RGD
located in lamellipodium IDA
IDA: Inferred from direct assay
25869297 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
14991772 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily V member 2

  • OTRPC2

  • VRL-1

  • osm-9-like TRP channel 2

  • stretch-activated channel 2B

  • vanilloid receptor-like protein 1

Trpv2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Trpv2 Q9WUD2 Trpv2 Rattus norvegicus Q9WUD2
Comig Non-Denat Gel
24373766
Intra
Trpv2 Q9WUD2 Trpv2 Rattus norvegicus Q9WUD2
GMS
24373766
Intra
Trpv2 Q9WUD2 Trpv2 Rattus norvegicus Q9WUD2
3D-EM
24373766
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0545 Probenecid Agonist 99.94% Yes

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-132222 SET2 Antagonist 99.78% Unkown
HY-157131 TRPV2-selective blocker 1 Inhibitor 99.84% Unkown
HY-182896 HKC54 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpv2 NCBI NCBI:51393