ATN1 - Atn1 atrophin 1 Gene

Also Known as Drpla

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29515

Summary

Enables JUN kinase binding activity. Involved in regulation of neuron differentiation. Located in cell leading edge; nucleus; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in dentatorubral-pallidoluysian atrophy and schizophrenia. Orthologous to human ATN1 (atrophin 1). [provided by Alliance of Genome Resources, Apr 2022]

ATN1 Products (2)

mRNA Protein Name
NM_001394346.1 NP_001381275.1 atrophin-1
NM_017228.3 NP_058924.2 atrophin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables JUN kinase binding IMP
IMP: Inferred from mutant phenotype
12812981 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10332026 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
12812981 RGD
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
19131340 RGD
located in nucleus IDA
IDA: Inferred from direct assay
19131340 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19131340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

atrophin-1

  • atrophin-1-like

  • dentatorubral pallidoluysian atrophy

  • dentatorubral-pallidoluysian atrophy protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01164 ATN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATN1 NCBI NCBI:1822