2. Gene
  3. Dync2li1 - dynein cytoplasmic 2 light intermediate chain 1 Gene

Dync2li1 - dynein cytoplasmic 2 light intermediate chain 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1310286

Gene ID: 298767 | Gene type: protein coding

About Dync2li1

Summary

Enables dynein heavy chain binding activity. Predicted to be involved in intraciliary retrograde transport; intraciliary transport involved in cilium assembly; and regulation of cilium assembly. Predicted to act upstream of or within cilium assembly and determination of left/right symmetry. Predicted to be located in several cellular components, including centrosome; ciliary transition zone; and motile cilium. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in axoneme and ciliary basal body. Predicted to colocalize with cytoplasmic microtubule. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Dync2li1 Products(1)

mRNA Protein Name
NM_001395083.1 NP_001382012.1 cytoplasmic dynein 2 light intermediate chain 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables dynein heavy chain binding IPI
IPI: Inferred from physical interaction
12432068 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic dynein 2 light intermediate chain 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04087 DYNC2LI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dync2li1 NCBI NCBI:51626