2. Gene
  3. Myo1a - myosin IA Gene

Myo1a - myosin IA Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as BBMI; MIHC; Myh1; Myhl

Gene ID: 299509 | Gene type: protein coding

About Myo1a

Summary

Predicted to enable actin filament binding activity and microfilament motor activity. Involved in regulation of protein localization. Located in several cellular components, including brush border; growth cone; and membrane raft. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 48 and sensorineural hearing loss. Orthologous to human MYO1A (Myosin IA). [provided by Alliance of Genome Resources, Apr 2022]

Myo1a Products(1)

mRNA Protein Name
NM_019324.1 NP_062197.1 unconventional myosin-Ia
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15138292 RGD
Biological Process GO Annotation Evidence Reference Source
involved in regulation of protein localization IMP
IMP: Inferred from mutant phenotype
15138292 RGD
Cellular Component GO Annotation Evidence Reference Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
8635202 RGD
located in brush border IDA
IDA: Inferred from direct assay
15138292 RGD
located in cell leading edge IDA
IDA: Inferred from direct assay
8635202 RGD
located in growth cone IDA
IDA: Inferred from direct assay
8635202 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
8635202 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ia

BBM-I

brush border myosin I

myosin I heavy chain

myosin heavy polypeptide 1 skeletal muscle adult

myosin, heavy polypeptide-like (110kD)

myosin-Ia

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08937 MYO1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1a NCBI NCBI:4640