Rnf7 - ring finger protein 7 Gene

Predicted to enable NEDD8 Ligase activity; cullin family protein binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in protein neddylation; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; brain development; and intrinsic apoptotic signaling pathway in response to oxidative stress. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of Cul5-RING ubiquitin Ligase complex. Predicted to be active in nucleus. Orthologous to human RNF7 (ring finger protein 7). [provided by Alliance of Genome Resources, Apr 2022]