2. Gene
  3. Abca12 - ATP binding cassette subfamily A member 12 Gene

Abca12 - ATP binding cassette subfamily A member 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 301482 | Gene type: protein coding

About Abca12

Summary

Predicted to enable ATPase-coupled transmembrane transporter activity; Apolipoprotein A-I receptor binding activity; and lipid transporter activity. Predicted to be involved in several processes, including corneocyte desquamation; phospholipid efflux; and positive regulation of intracellular lipid transport. Predicted to act upstream of or within several processes, including positive regulation of Cholesterol efflux; positive regulation of protein localization to cell surface; and skin development. Predicted to be located in bounding membrane of organelle; cytosol; and plasma membrane. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1; autosomal recessive congenital ichthyosis 4A; and autosomal recessive congenital ichthyosis 4B. Orthologous to human ABCA12 (ATP binding cassette subfamily A member 12). [provided by Alliance of Genome Resources, Apr 2022]

Abca12 Products(3)

mRNA Protein Name
XM_237242.11 XP_237242.6 ATP-binding cassette sub-family A member 12 isoform X1
XM_039084631.1 XP_038940559.1 ATP-binding cassette sub-family A member 12 isoform X3
XM_039084630.1 XP_038940558.1 ATP-binding cassette sub-family A member 12 isoform X2
Protein Preferred Names Protein Names

ATP-binding cassette sub-family A member 12

ATP-binding cassette, sub-family A (ABC1), member 12

ATP-binding cassette, subfamily A (ABC1), member 12

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00039 ABCA12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abca12 NCBI NCBI:26154