Kcnt2 - potassium sodium-activated channel subfamily T member 2 Gene

Also Known as Slick

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304827

Summary

Enables chloride-activated Potassium Channel activity. Involved in potassium ion export across plasma membrane. Acts upstream of or within potassium ion transport. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 57. Orthologous to human KCNT2 (potassium sodium-activated channel subfamily T member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnt2 Products (1)

mRNA Protein Name
NM_198762.2 NP_942057.2 potassium channel subfamily T member 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chloride-activated potassium channel activity IMP
IMP: Inferred from mutant phenotype
29069600 RGD
enables potassium channel activity IDA
IDA: Inferred from direct assay
14684870 RGD
Biological Process GO Annotation Evidence References Source
involved in potassium ion export across plasma membrane IMP
IMP: Inferred from mutant phenotype
29069600 RGD
acts upstream of or within potassium ion transport IDA
IDA: Inferred from direct assay
14684870 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily T member 2

  • potassium channel, sodium-activated subfamily T, member 2

  • potassium channel, subfamily T, member 2

  • sequence like an intermediate conductance potassium channel subunit

  • sodium and chloride-activated ATP-sensitive potassium channel Slo2.1

  • sodium- and chl

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162549 CPK20 Inhibitor 99.67% Unkown
HY-RS07182 KCNT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P0058S Pramlintide-(Ala-13C3,15N) / Unkown
HY-RS22591 Kcnt2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnt2 NCBI NCBI:343450