Mcph1 - microcephalin 1 Gene

Rattus norvegicus

Also known as RGD1560642

Gene ID: 306594 | Gene type: protein coding

About Mcph1

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in mitotic cell cycle and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including establishment of mitotic spindle orientation; neuronal stem cell population maintenance; and protein localization to centrosome. Predicted to be located in microtubule organizing center. Human ortholog(s) of this gene implicated in breast cancer; endometrial cancer; microcephaly; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 1. Orthologous to human MCPH1 (microcephalin 1). [provided by Alliance of Genome Resources, Apr 2022]

Mcph1 Products(3)

mRNA	Protein	Name
XM_006253383.4	XP_006253445.1	microcephalin isoform X2
XM_225006.10	XP_225006.7	microcephalin isoform X1
XM_006253385.4	XP_006253447.1	microcephalin isoform X3

Protein Preferred Names

Protein Names

microcephalin

microcephaly, primary autosomal recessive 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08247	MCPH1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mcph1	NCBI	NCBI:79648

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