2. Gene
  3. Afg3l2 - AFG3 like matrix AAA peptidase subunit 2 Gene

Afg3l2 - AFG3 like matrix AAA peptidase subunit 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 307350 | Gene type: protein coding

About Afg3l2

Summary

Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including calcium import into the mitochondrion; mitochondrial calcium ion homeostasis; and proteolysis. Predicted to act upstream of or within several processes, including mitochondrion organization; nervous system development; and righting reflex. Located in mitochondrion. Human ortholog(s) of this gene implicated in optic atrophy 12; spastic ataxia; spastic ataxia 5; and spinocerebellar ataxia type 28. Orthologous to human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Afg3l2 Products(1)

mRNA Protein Name
NM_001134864.1 NP_001128336.1 AFG3-like protein 2
Protein Preferred Names Protein Names

AFG3-like protein 2

AFG3 ATPase family member 3-like 2

AFG3-like AAA ATPase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00432 AFG3L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Afg3l2 NCBI NCBI:10939