2. Gene
  3. WDR62 - Wdr62 WD repeat domain 62 Gene

WDR62 - Wdr62 WD repeat domain 62 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1306714

Gene ID: 308492 | Gene type: protein coding

About WDR62

Summary

Involved in several processes, including positive regulation of neuroblast proliferation; positive regulation of neuron migration; and regulation of centrosome cycle. Predicted to be located in centriolar satellite and cytosol. Predicted to be active in nucleus and spindle pole. Human ortholog(s) of this gene implicated in intellectual disability; polymicrogyria; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 2 with or without cortical malformations. Orthologous to human WDR62 (WD repeat domain 62). [provided by Alliance of Genome Resources, Apr 2022]

WDR62 Products(1)

mRNA Protein Name
NM_001191623.2 NP_001178552.2 WD repeat-containing protein 62
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
24388750 RGD
involved in positive regulation of neuron migration IMP
IMP: Inferred from mutant phenotype
24388750 RGD
involved in regulation of centrosome cycle IMP
IMP: Inferred from mutant phenotype
24388750 RGD
involved in regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
24388750 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat-containing protein 62

WD repeat domain 62-like 1

WD repeat-containing protein 62-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15791 WDR62 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens WDR62 NCBI NCBI:284403