Shoc2 - SHOC2 leucine-rich repeat scaffold protein Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309548

Summary

Predicted to enable protein Phosphatase 1 binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction and signal transduction. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein Phosphatase type 1 complex. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 1. Orthologous to human SHOC2 (SHOC2 leucine rich repeat scaffold protein). [provided by Alliance of Genome Resources, Apr 2022]

Shoc2 Products (1)

mRNA Protein Name
NM_001013155.2 NP_001013173.1 leucine-rich repeat protein SHOC-2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to growth hormone stimulus IEP
IEP: Inferred from expression pattern
15300589 RGD
involved in negative regulation of neural precursor cell proliferation IMP
IMP: Inferred from mutant phenotype
21732489 RGD
involved in negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
21732489 RGD
involved in nerve growth factor signaling pathway IMP
IMP: Inferred from mutant phenotype
25514808 RGD
involved in positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
25514808 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
25514808 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat protein SHOC-2

  • protein soc-2 homolog

  • protein sur-8 homolog

  • soc-2 (suppressor of clear) homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-202699 SHOC2-RAS PPI-IN-1 Inhibitor 99.50% Unkown
HY-RS12878 SHOC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shoc2 NCBI NCBI:8036