RT1-Ba - RT1 class II, locus Ba Gene

Also Known as BA1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309621

Summary

Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Involved in cellular response to glucocorticoid stimulus and negative regulation of T cell proliferation. Predicted to be located in external side of plasma membrane and lysosome. Predicted to be part of MHC class II protein complex. Used to study uveitis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system Cancer (multiple); glomerulonephritis (multiple); hematologic Cancer (multiple); and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

RT1-Ba Products (1)

mRNA Protein Name
NM_001008831.3 NP_001008831.1 rano class II histocompatibility antigen, B alpha chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
2465490 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to glucocorticoid stimulus IEP
IEP: Inferred from expression pattern
12034349 RGD
involved in negative regulation of T cell proliferation IDA
IDA: Inferred from direct assay
9834080 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rano class II histocompatibility antigen, B alpha chain

  • MHC class I antigen

  • MHC class II antigen RT1.B alpha chain

  • RT1 class II antigen, Ba chain

  • RT1-B alpha

  • activated B cell RT1Bl alpha chain