Eps8 - epidermal growth factor receptor pathway substrate 8 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312812

Summary

Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; actin filament organization; and barbed-end actin filament capping. Predicted to act upstream of or within several processes, including actin Cytoskeleton reorganization; behavioral response to ethanol; and cellular response to Leukemia Inhibitory Factor. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (epidermal growth factor receptor pathway substrate 8). [provided by Alliance of Genome Resources, Apr 2022]

Eps8 Products (1)

mRNA Protein Name
NM_001376935.1 NP_001363864.1 epidermal growth factor receptor kinase substrate 8

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17223277 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
17223277 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

epidermal growth factor receptor kinase substrate 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04454 EPS8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P10994 Eps8 peptide 327 / Unkown
HY-P10995 TAT-327 / Unkown
HY-P11076 CP-EPS8-NLS Inhibitor / Unkown
HY-RS04455 EPS8L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04456 EPS8L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04457 EPS8L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20154 Eps8l1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26658 Eps8l1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eps8 NCBI NCBI:2059