2. Gene
  3. Rap1gap - Rap1 GTPase-activating protein Gene

Rap1gap - Rap1 GTPase-activating protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rap1ga1

Gene ID: 313644 | Gene type: protein coding

About Rap1gap

Summary

Predicted to enable GTPase activator activity; protein homodimerization activity; and small GTPase binding activity. Involved in several processes, including cellular response to glial cell derived neurotrophic factor; negative regulation of GTP binding activity; and negative regulation of thyroid gland epithelial cell proliferation. Located in several cellular components, including dendrite; early endosome; and neuronal cell body. Orthologous to human RAP1GAP (RAP1 GTPase activating protein). [provided by Alliance of Genome Resources, Apr 2022]

Rap1gap Products(1)

mRNA Protein Name
NM_001100713.1 NP_001094183.1 rap1 GTPase-activating protein 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to glial cell derived neurotrophic factor IDA
IDA: Inferred from direct assay
20877310 RGD
involved in negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
20877310 RGD
involved in negative regulation of thyroid gland epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
17646383 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
20877310 RGD
located in dendrite IDA
IDA: Inferred from direct assay
20877310 RGD
located in early endosome IDA
IDA: Inferred from direct assay
20877310 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
20877310 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rap1 GTPase-activating protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11654 RAP1GAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11655 RAP1GAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22068 Rap1gap2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28586 Rap1gap2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rap1gap NCBI NCBI:5909