2. Gene
  3. HOXD1 - homeobox D1 Gene

HOXD1 - homeobox D1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HOX4; HOX4G; Hox-4.7

Gene ID: 3231 | Gene type: protein coding

About HOXD1

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:176,188,668-176,190,907 (from NCBI)

This gene has 1 transcript (splice variant), 110 orthologues and 42 paralogues. Broad expression in kidney (RPKM 1.7), lung (RPKM 1.6) and 16 other tissues.

Summary

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]

HOXD1 Products(1)

mRNA Protein Name
NM_024501.3 NP_078777.1 homeobox protein Hox-D1

HOXD1 Protein Structure

Homeobox

Homeobox: Homeobox domain (233 - 286)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
Protein Preferred Names Protein Names

homeobox protein Hox-D1

homeo box 4G

Related Diseases

Diseases Alias
Synpolydactyly

Syndactyly Type 2

Syndactyly, Type 2

Spd
Clubfoot

Congenital Talipes Equinovarus

Congenital Clubfoot

Congenital Equinovarus

Equinovarus Deformity Of Foot

Club Foot
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06322 HOXD1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HOXD1 MGD MGI:96201
Rattus norvegicus HOXD1 RGD RGD:1309179
Macaca mulatta HOXD1 VGNC VGNC:104536
Bos taurus HOXD1 VGNC VGNC:29929
Canis familiaris HOXD1 VGNC VGNC:41761
Felis catus HOXD1 VGNC VGNC:107557