Dnah2 - dynein, axonemal, heavy chain 2 Gene

Also Known as Dnhd3; Dnahc2; 4930564A01; D130094J20; 2900022L05Rik; D330014H01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 327954

Summary

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium-dependent cell motility and microtubule-based movement. Located in motile cilium. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in spermatogenic failure 45. Orthologous to human DNAH2 (dynein axonemal heavy chain 2). [provided by Alliance of Genome Resources, Apr 2022]

Dnah2 Products (1)

mRNA Protein Name
NM_001081330.1 NP_001074799.1 dynein axonemal heavy chain 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cilium movement IMP
IMP: Inferred from mutant phenotype
30060180 MGI
Cellular Component GO Annotation Evidence References Source
part of axonemal dynein complex IDA
IDA: Inferred from direct assay
30060180 MGI
located in cilium IDA
IDA: Inferred from direct assay
30060180 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
10330409 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein axonemal heavy chain 2

dynein heavy chain 2, axonemal

  • axonemal beta dynein heavy chain 2

  • axonemal dynein heavy chain

  • ciliary dynein heavy chain 2

  • dynein heavy chain domain 3

  • dynein, axon, heavy chain 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03848 DNAH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnah2 NCBI NCBI:146754