2. Gene
  3. Hfm1 - HFM1, ATP-dependent DNA helicase homolog Gene

Hfm1 - HFM1, ATP-dependent DNA helicase homolog Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mer3; Gm1046; Sec63d1; A330009G12Rik

Gene ID: 330149 | Gene type: protein coding

About Hfm1

Summary

Predicted to enable DNA helicase activity. Acts upstream of or within resolution of meiotic recombination intermediates. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 9. Orthologous to human HFM1 (helicase for meiosis 1). [provided by Alliance of Genome Resources, Apr 2022]

Hfm1 Products(5)

mRNA Protein Name
NM_001252516.2 NP_001239445.1 probable ATP-dependent DNA helicase HFM1 isoform 2
NM_001412542.1 NP_001399471.1 probable ATP-dependent DNA helicase HFM1 isoform 3
NM_001412561.1 NP_001399490.1 probable ATP-dependent DNA helicase HFM1 isoform 4
NM_001412562.1 NP_001399491.1 probable ATP-dependent DNA helicase HFM1 isoform 5
NM_177873.4 NP_808541.2 probable ATP-dependent DNA helicase HFM1 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within resolution of meiotic recombination intermediates IMP
IMP: Inferred from mutant phenotype
23555294 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable ATP-dependent DNA helicase HFM1

SEC63 domain containing 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06150 HFM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hfm1 NCBI NCBI:164045