Slc51b - solute carrier family 51, beta subunit Gene

Mus musculus

Also known as Ostb

Gene ID: 330962 | Gene type: protein coding

About Slc51b

Summary

Enables bile acid transmembrane transporter activity and protein heterodimerization activity. Involved in several processes, including bile acid and bile salt transport; positive regulation of intracellular protein transport; and positive regulation of protein glycosylation. Acts upstream of or within organic substance transport. Located in basolateral plasma membrane. Is integral component of membrane. Part of protein-containing complex. Is expressed in small intestine. Orthologous to human SLC51B (solute carrier family 51 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Slc51b Products(1)

mRNA	Protein	Name
NM_178933.2	NP_849264.1	organic solute transporter subunit beta

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables bile acid transmembrane transporter activity	IPI IPI: Inferred from physical interaction	16317684	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	17650074	MGI
enables protein heterodimerization activity	IDA IDA: Inferred from direct assay	17650074	MGI
enables transmembrane transporter activity	IPI IPI: Inferred from physical interaction	12719432	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in bile acid and bile salt transport	IDA IDA: Inferred from direct assay	17650074	MGI
involved in bile acid and bile salt transport	IPI IPI: Inferred from physical interaction	16317684	MGI
involved in positive regulation of protein exit from endoplasmic reticulum	IDA IDA: Inferred from direct assay	17650074	MGI
involved in positive regulation of protein glycosylation	IDA IDA: Inferred from direct assay	22535958	MGI
involved in positive regulation of protein targeting to membrane	IDA IDA: Inferred from direct assay	17650074	MGI
involved in regulation of protein stability	IDA IDA: Inferred from direct assay	22535958	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	16317684	MGI
located in membrane	IDA IDA: Inferred from direct assay	17650074	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	17650074	MGI
part of protein-containing complex	IDA IDA: Inferred from direct assay	17650074	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

organic solute transporter subunit beta

OST-beta	Ost beta
organic solute transporter beta	solute carrier family 51 subunit beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13276	SLC51B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc51b	NCBI	NCBI:123264

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