Sgms1 - sphingomyelin synthase 1 Gene

Also Known as Mob; mob-1; Tmem23

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 353229

Summary

Predicted to enable ceramide cholinephosphotransferase activity; ceramide phosphoethanolamine synthase activity; and sphingomyelin synthase activity. Involved in several processes, including cellular response to lipopolysaccharide; cellular response to tumor necrosis factor; and inflammatory response. Predicted to be located in Golgi trans cisterna. Predicted to be integral component of Golgi membrane; integral component of endoplasmic reticulum membrane; and integral component of plasma membrane. Used to study pulmonary edema. Biomarker of pulmonary edema. Orthologous to human SGMS1 (sphingomyelin synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sgms1 Products (1)

mRNA Protein Name
NM_181386.3 NP_852051.2 phosphatidylcholine:ceramide cholinephosphotransferase 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
12353928 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
12353928 RGD
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
12353928 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylcholine:ceramide cholinephosphotransferase 1

  • protein Mob

  • transmembrane protein 23

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12805 SGMS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgms1 NCBI NCBI:259230