1. Gene
  2. Hba-a2 - hemoglobin alpha, adult chain 2 Gene

Hba-a2 - hemoglobin alpha, adult chain 2 Gene

Rattus norvegicus

Also known as Hba1; Hba2; Glnc2; Glnc3; Hba-a1

Gene ID: 360504 | Gene type: protein coding

About Hba-a2

Summary

Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Involved in response to estradiol. Predicted to be located in extracellular space. Predicted to be part of cytosolic small ribosomal subunit; haptoglobin-hemoglobin complex; and Hemoglobin complex. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and Hemoglobin H disease. Orthologous to several human genes including HBA2 (Hemoglobin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Hba-a2 Products(1)

mRNA Protein Name
NM_001007722.2 NP_001007723.1 hemoglobin alpha, adult chain 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables G protein-coupled receptor binding IDA
IDA: Inferred from direct assay
18077343 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12072504 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to estradiol IEP
IEP: Inferred from expression pattern
20534718 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hemoglobin alpha, adult chain 2

2-alpha globin

2-alpha-1 globin

Alpha-1/2-globin

Hemoglobin alpha-1/2 chain

Hemoglobin subunit alpha-1/2

globin c2

globin c3

hemoglobin alpha 2 chain

hemoglobin, alpha 2