2. Gene
  3. DHTKD1 - Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 Gene

DHTKD1 - Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as E1a; OADC-E1; OADH-E1

Gene ID: 361272 | Gene type: protein coding

About DHTKD1

Summary

Predicted to enable oxoglutarate dehydrogenase (succinyl-transferring) activity and thiamine pyrophosphate binding activity. Predicted to be involved in generation of precursor metabolites and energy. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth disease axonal type 2Q. Orthologous to human DHTKD1 (dehydrogenase E1 and Transketolase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

DHTKD1 Products(1)

mRNA Protein Name
NM_001025720.1 NP_001020891.1 2-oxoadipate dehydrogenase complex component E1
Protein Preferred Names Protein Names

2-oxoadipate dehydrogenase complex component E1

probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial

2-oxoadipate dehydrogenase, mitochondrial

alpha-KADH-E1

alpha-ketoadipate dehydrogenase

dehydrogenase E1 and transketolase domain-containing protein 1

probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03747 DHTKD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21844 Dhtkd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DHTKD1 NCBI NCBI:55526