Gnat1 - G protein subunit alpha transducin 1 Gene

Also Known as Hg1f

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363143

Summary

Enables GTP binding activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of bitter taste; positive regulation of cyclic-nucleotide phosphodiesterase activity; and rhodopsin mediated signaling pathway. Located in several cellular components, including apical plasma membrane; photoreceptor inner segment; and photoreceptor outer segment. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1G; congenital stationary night blindness autosomal dominant 3; and night blindness. Orthologous to human GNAT1 (G protein subunit alpha transducin 1). [provided by Alliance of Genome Resources, Apr 2022]

Gnat1 Products (1)

mRNA Protein Name
NM_001108780.2 NP_001102250.2 guanine nucleotide-binding protein G(t) subunit alpha-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTP binding IDA
IDA: Inferred from direct assay
7596440 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18028335 RGD
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled opsin signaling pathway IMP
IMP: Inferred from mutant phenotype
11931744 RGD
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: Inferred from direct assay
7596440 RGD
involved in positive regulation of cyclic-nucleotide phosphodiesterase activity IDA
IDA: Inferred from direct assay
7878085 RGD
involved in response to light intensity IDA
IDA: Inferred from direct assay
11931744 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17495045 RGD
part of heterotrimeric G-protein complex IDA
IDA: Inferred from direct assay
11931744 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
11931744 RGD
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
11931744 RGD
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
10396627 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(t) subunit alpha-1

  • guanine nucleotide binding protein (G protein), alpha transducing 1

  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

  • guanine nucleotide binding protein, alpha transducing 1

  • heterotrimeric guanine nucleotide-bindi

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05541 GNAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnat1 NCBI NCBI:2779