FGD1 - Fgd1 FYVE, RhoGEF and PH domain containing 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363460

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within Cytoskeleton organization. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Human ortholog(s) of this gene implicated in X-linked Aarskog syndrome and non-syndromic X-linked intellectual disability. Orthologous to human FGD1 (FYVE, RhoGEF and PH domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

FGD1 Products (2)

mRNA Protein Name
NM_001037546.1 NP_001032635.1 FYVE, RhoGEF and PH domain-containing protein 1 isoform 2
NM_001414732.1 NP_001401661.1 FYVE, RhoGEF and PH domain-containing protein 1 isoform 1
Protein Preferred Names Protein Names

FYVE, RhoGEF and PH domain-containing protein 1

  • FYVE, RhoGEF and PH domain-containing protein 1-like

Orthologs Information

Species Symbol Source ID
Homo sapiens FGD1 NCBI NCBI:2245