2. Gene
  3. FGD1 - Fgd1 FYVE, RhoGEF and PH domain containing 1 Gene

FGD1 - Fgd1 FYVE, RhoGEF and PH domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 363460 | Gene type: protein coding

About FGD1

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within Cytoskeleton organization. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Human ortholog(s) of this gene implicated in X-linked Aarskog syndrome and non-syndromic X-linked intellectual disability. Orthologous to human FGD1 (FYVE, RhoGEF and PH domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

FGD1 Products(2)

mRNA Protein Name
NM_001037546.1 NP_001032635.1 FYVE, RhoGEF and PH domain-containing protein 1 isoform 2
NM_001414732.1 NP_001401661.1 FYVE, RhoGEF and PH domain-containing protein 1 isoform 1
Protein Preferred Names Protein Names

FYVE, RhoGEF and PH domain-containing protein 1

FYVE, RhoGEF and PH domain-containing protein 1-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04880 FGD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FGD1 NCBI NCBI:2245