Myl2 - myosin light chain 2 Gene

Also Known as Mlc2; Mlc-2; MLC-2s/v

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363925

Summary

Predicted to enable actin monomer binding activity and calcium ion binding activity. Involved in cardiac muscle contraction; cell growth involved in cardiac muscle cell development; and regulation of the force of heart contraction. Located in myofibril. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy and hypertrophic cardiomyopathy 10. Orthologous to human MYL2 (Myosin light chain 2). [provided by Alliance of Genome Resources, Apr 2022]

Myl2 Products (1)

mRNA Protein Name
NM_001035252.2 NP_001030329.2 myosin regulatory light chain 2, ventricular/cardiac muscle isoform

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cardiac muscle contraction IDA
IDA: Inferred from direct assay
11448842 RGD
involved in cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
9409484 RGD
involved in cell growth involved in cardiac muscle cell development IEP
IEP: Inferred from expression pattern
7657802 RGD
involved in regulation of the force of heart contraction IDA
IDA: Inferred from direct assay
15331360 RGD
Cellular Component GO Annotation Evidence References Source
located in contractile muscle fiber IDA
IDA: Inferred from direct assay
9409484 RGD
located in myofibril IDA
IDA: Inferred from direct assay
11448842 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin regulatory light chain 2, ventricular/cardiac muscle isoform

  • cardiac myosin light chain-2

  • myosin, light chain 2, regulatory, cardiac, slow

  • myosin, light polypeptide 2, regulatory, cardiac, slow

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08914 MYL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myl2 NCBI NCBI:4633