Gnat2 - G protein subunit alpha transducin 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 365901

Summary

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of bitter taste; positive regulation of cytosolic calcium ion concentration; and response to light intensity. Located in photoreceptor inner segment and photoreceptor outer segment. Human ortholog(s) of this gene implicated in achromatopsia 4 and color blindness. Orthologous to human GNAT2 (G protein subunit alpha transducin 2). [provided by Alliance of Genome Resources, Apr 2022]

Gnat2 Products (1)

mRNA Protein Name
NM_001108950.2 NP_001102420.2 guanine nucleotide-binding protein G(t) subunit alpha-2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12917372 RGD
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: Inferred from direct assay
12917372 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
12917372 RGD
involved in response to light intensity IDA
IDA: Inferred from direct assay
17591908 RGD
Cellular Component GO Annotation Evidence References Source
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
17591908 RGD
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
17591908 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(t) subunit alpha-2

  • guanine nucleotide binding protein (G protein), alpha transducing 2

  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2

  • guanine nucleotide binding protein, alpha transducing 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05542 GNAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnat2 NCBI NCBI:2780