Crb2 - crumbs cell polarity complex component 2 Gene

Rattus norvegicus

Also known as RGD1309368

Gene ID: 366031 | Gene type: protein coding

About Crb2

Summary

Predicted to enable aspartic-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including embryonic morphogenesis; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and maintenance of epithelial cell apical/basal polarity. Predicted to be located in several cellular components, including apical plasma membrane; apicolateral plasma membrane; and cell junction. Predicted to be part of subapical complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 9 and ventriculomegaly - cystic kidney disease. Orthologous to human CRB2 (crumbs cell polarity complex component 2). [provided by Alliance of Genome Resources, Apr 2022]

Crb2 Products(1)

mRNA	Protein	Name
NM_001135761.2	NP_001129233.1	protein crumbs homolog 2 precursor

Protein Preferred Names

Protein Names

protein crumbs homolog 2

crumbs 2, cell polarity complex component

crumbs family member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03141	CRB2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Crb2	NCBI	NCBI:286204

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