Dock4 - dedicator of cytokinesis 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 366608

Summary

Predicted to enable PDZ domain binding activity; enzyme binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in cell chemotaxis; negative regulation of vascular associated smooth muscle contraction; and positive regulation of vascular associated smooth muscle cell migration. Predicted to be located in several cellular components, including Golgi apparatus; nucleolus; and stereocilium. Orthologous to human DOCK4 (dedicator of cytokinesis 4). [provided by Alliance of Genome Resources, Apr 2022]

Dock4 Products (6)

mRNA Protein Name
XM_039078124.1 XP_038934052.1 dedicator of cytokinesis protein 4 isoform X1
XM_039078129.1 XP_038934057.1 dedicator of cytokinesis protein 4 isoform X5
XM_039078128.1 XP_038934056.1 dedicator of cytokinesis protein 4 isoform X4
XM_039078126.1 XP_038934054.1 dedicator of cytokinesis protein 4 isoform X3
XM_039078130.1 XP_038934058.1 dedicator of cytokinesis protein 4 isoform X6
XM_039078125.1 XP_038934053.1 dedicator of cytokinesis protein 4 isoform X2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
23536706 RGD
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
23536706 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23536706 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23536706 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
23536706 RGD
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
23536706 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dedicator of cytokinesis 4

dedicator of cytokinesis protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03926 DOCK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dock4 NCBI NCBI:9732