2. Gene
  3. SYNE2 - Syne2 spectrin repeat containing nuclear envelope protein 2 Gene

SYNE2 - Syne2 spectrin repeat containing nuclear envelope protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1305248; AABR07064873.1

Gene ID: 366669 | Gene type: protein coding

About SYNE2

Summary

Predicted to enable actin binding activity and cytoskeleton-nuclear membrane anchor activity. Predicted to be involved in several processes, including centrosome localization; nuclear migration; and regulation of cilium assembly. Predicted to act upstream of or within several processes, including fibroblast migration; nuclear envelope organization; and protein localization to nucleus. Predicted to be located in several cellular components, including cell projection membrane; focal adhesion; and nucleus. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Used to study cryptorchidism. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 5. Orthologous to human SYNE2 (spectrin repeat containing nuclear envelope protein 2). [provided by Alliance of Genome Resources, Apr 2022]

SYNE2 Products(13)

mRNA Protein Name
XM_039113266.1 XP_038969194.1 nesprin-2 isoform X7
XM_039113258.1 XP_038969186.1 nesprin-2 isoform X1
XM_039113264.1 XP_038969192.1 nesprin-2 isoform X5
XM_039113263.1 XP_038969191.1 nesprin-2 isoform X4
XM_039113268.1 XP_038969196.1 nesprin-2 isoform X9
XM_039113261.1 XP_038969189.1 nesprin-2 isoform X2
XM_039113262.1 XP_038969190.1 nesprin-2 isoform X3
XM_039113267.1 XP_038969195.1 nesprin-2 isoform X8
XM_039113269.1 XP_038969197.1 nesprin-2 isoform X10
XM_039113260.1 XP_038969188.1 nesprin-2 isoform X1
XM_039113259.1 XP_038969187.1 nesprin-2 isoform X1
XM_039113265.1 XP_038969193.1 nesprin-2 isoform X6
XM_039113270.1 XP_038969198.1 nesprin-2 isoform X11
Protein Preferred Names Protein Names

nesprin-2

spectrin repeat containing nuclear envelope protein 2

nesprin-2-like

spectrin repeat containing, nuclear envelope 2

synaptic nuclear envelope 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14086 SYNE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SYNE2 NCBI NCBI:23224