Col27a1 - collagen, type XXVII, alpha 1 Gene

Also Known as 5730512J02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 373864

Summary

This gene encodes the alpha-1 subunit of type XXVII Collagen, one of the low abundance fibril-forming collagens found in cartilage. The encoded protein forms a homotrimeric triple helical procollagen that undergoes proteolytic processing during fibril formation. Transgenic mice lacking a portion of the collagenous domain in the encoded protein exhibit skeletal abnormalities, chondrodysplasia and die at birth because of a lung defect. [provided by RefSeq, Dec 2015]

Col27a1 Products (1)

mRNA Protein Name
NM_025685.3 NP_079961.3 collagen alpha-1(XXVII) chain preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables extracellular matrix structural constituent IDA
IDA: Inferred from direct assay
22206015 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
22206015 MGI
acts upstream of or within growth plate cartilage chondrocyte development IMP
IMP: Inferred from mutant phenotype
22206015 MGI
Cellular Component GO Annotation Evidence Verweise Source
part of fibrillar collagen trimer IDA
IDA: Inferred from direct assay
17331945 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-1(XXVII) chain

  • procollagen, type XXVII, alpha 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02979 COL27A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col27a1 NCBI NCBI:85301